Treatments Plot

From Glioblastoma Treatments
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Treatment NameUsefulness RatingToxicity LevelCategory
ABT-41424Antibody-Drug Conjugates and other protein-drug conjugates
Isotretinoin (Accutane)33Repurposed Drugs
Agenus Prophage (Heat-Shock Protein Peptide Complex-96) Vaccine42General
Angiotensin-II Receptor Blockers (ARB)32Hormones
Angiotensin-Il Receptor Blockers (ARB)Not ratedNot specifiedHormones and Cancer Therapy
Anlotinib43General
Anti-CMV Dendritic Cell Vaccine42Tumor-associated antigen vaccines
BCNU (Carmustine)Pending review of recent clinical trials and comparative studies4Other chemotherapy agents at recurrence
BCNU (Carmustine) and Gliadel (Carmustine Wafers)44Other Chemotherapy and Cancer Drugs
Beta-blockers (especially propranolol) and the role of the sympatheticNot ratedNot specifiedHormones and Cancer Therapy
Bevacizumab (Avastin)43Other Chemotherapy and Cancer Drugs
CBD (Cannabidiol)42Nutraceuticals
Cannabigerol (CBG)32Nutraceuticals
CCNU (Lomustine)44Other Chemotherapy and Cancer Drugs
CPT-11 (Irinotecan)Under investigation; early results promising, especially in combination therapies3Other chemotherapy agents at recurrence
Cannabis and Cannabis-derived Products (e.g., Sativex)41Nutraceuticals
CarboplatinPending further clinical trials and data2Other chemotherapy agents at recurrence
Celebrex (Celecoxib) and Other NSAIDs32.5Repurposed Drugs
Chloroquine and Hydroxychloroquine41Repurposed Drugs
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Chloroquine and HydroxychloroquineNot ratedNot specifiedRepurposed Drugs
Chronotherapy with Temozolomide (TMZ)4Comparable to standard TMZ treatments, but timing affects management of side effects.General
Curcumin31Nutraceuticals
DNX-2401 adenovirusNot ratedNot specifiedOncolytic virotherapy
Dendritic Cell Vaccine (DCVax-L)42General
Disulfiram (Antabuse)32Repurposed Drugs
EGFR Inhibitors (Tarceva, Erbitux) in combination with Stupp Protocol32General
Ellagic Acid31Nutraceuticals
Fish Oil (Omega-3 Fatty Acids: EPA and DHA)41Nutraceuticals
FotemustineBased on available data, potentially highly useful in specific dosing schedules3Other chemotherapy agents at recurrence
Gamma-Linolenic Acid (GLA)21Over-the-Counter Drugs and Supplements
Gamma Knife Radiosurgery (GKRS) for GBM32General
Garlic (Allium sativum)31Nutraceuticals
Genetically modified Poliovirus (PVS-RIPO)Not ratedNot specifiedOncolytic virotherapy
Gleevec (Imatinib)33Other Chemotherapy and Cancer Drugs
Herpes VirusNot ratedNot specifiedOncolytic virotherapy
Hyperthermia43General
ICT-107 (Tumor-associated Antigen Vaccine)42Tumor-associated antigen vaccines
Keppra (Levetiracetam)42Repurposed Drugs
Letrozole3 - Under investigation2.5Repurposed Drugs
Perillyl Alcohol/Limonene32Over-the-Counter Drugs and Supplements
MDNA5532.5Antibody-Drug Conjugates and other protein-drug conjugates
MN-166 (Ibudilast)3 (awaiting research)1Repurposed Drugs
Melatonin41Hormones and Cancer Therapy
Sodium R Lipoate and Hydroxycitrate (METABLOC)32Over-the-Counter Drugs and Supplements
Metformin32Repurposed Drugs
Methadone (D,L-methadone)32Repurposed Drugs
Metronomic Low-Dose Temozolomide (TMZ)43General
Newcastle Disease VirusNot ratedNot specifiedOncolytic virotherapy
Next-Generation CAR T-Cell Therapy for GBM43General
Optune (Optune Gio® for newer version)52Innovative Cancer Therapies
... further results