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From Glioblastoma Treatments
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Showing below up to 50 results in range #101 to #150.
- Gleevec (Imatinib) (2 links)
- High-dose PBT showed a median OS of 65.6 months for patients with radiation necrosis, and 26.9 months for patients without radiation necrosis in specific studies (2 links)
- Historical controls indicate median overall survival around 15-17 months for newly diagnosed GBM. (2 links)
- Historical controls suggest a median overall survival of 20-35% at 12 months for similar populations. (2 links)
- Historical mOS for similar patient population using lomustine is 7.2 months (2 links)
- Hyperthermia (2 links)
- ICT-107 (2 links)
- ICT-107 (Tumor-associated Antigen Vaccine) (2 links)
- Impressive 25.3 months in a study combining vaccine with dose-intense temozolomide. (2 links)
- Improved PFS observed with PBT, specific rates vary by study (2 links)
- Increases observed in specific combination trials, such as Irinotecan with Bevacizumab (2 links)
- Lower compared to traditional GBM treatments, with no significant radiation-induced toxicities reported in recent studies. (2 links)
- MDNA55 (2 links)
- Median overall survival for GBM typically ranges around 16 months with standard treatment. (2 links)
- Median overall survival with standard treatment ranges around 15-17 months for newly diagnosed GBM (2 links)
- Median progression-free survival with standard treatments is about 6-9 months for GBM (2 links)
- Metformin (2 links)
- Metronomic Low-Dose Temozolomide (TMZ) (2 links)
- Metronomic low dose temozolomide (TMZ) (2 links)
- Next-Generation CAR T-Cell Therapy for GBM (2 links)
- Not directly specified; historical control data needed for comprehensive comparison (2 links)
- Not directly specified; ongoing studies aim to clarify Carboplatin's impact on survival in recurrent glioma (2 links)
- Not fully established from available data (2 links)
- Not specified; however, survival six months after recurrence was used as a primary measure in comparative studies with Avastin (2 links)
- Not specified in the provided context (2 links)
- Optune (2 links)
- Optune (Optune Gio® for newer version) (2 links)
- Pending further clinical trials (2 links)
- Pending further clinical trials and data (2 links)
- Pending review of recent clinical trials and comparative studies (2 links)
- Phase III ACT IV trial did not show a significant increase in OS; however, a Phase II trial (ReACT) in recurrent GBM showed improved outcomes with bevacizumab (2 links)
- Phase II trial showed a significant improvement in PFS, particularly for HLA-A2 positive patients with methylated MGMT, showing a median PFS of 24.1 months vs. 8.5 months in the control group. (2 links)
- Platinum Compounds (2 links)
- Procarbazine (2 links)
- Radiation dermatitis, temporary alopecia, radiation otitis, radiation necrosis (more prevalent in PBT group) (2 links)
- Ranges from 26 to 44% with different schedules; 61% PFS-6 with the best results obtained using a specific dosing schedule (2 links)
- ReACT trial showed a 6-month PFS of 28% for the rindopepimut group compared to 16% for the control (2 links)
- SL-701 (2 links)
- SL-701 (Immunotherapy Vaccine) (2 links)
- Some studies report mean progression-free survival up to 17.2 months, compared to 4-10 months for other treatments (2 links)
- Stage 1 median overall survival was 11.0 months with a 12-month OS rate of 44%. Stage 2 showed a median OS of 11.7 months with a 12-month OS rate of 50%, suggesting an improvement over historical data. (2 links)
- Standard radiation therapy PFS rates are lower compared to PBT (2 links)
- Standard treatments for GBM typically result in a median overall survival of 14-17 months (2 links)
- Standard treatments offer a median PFS of about 6.9 months (2 links)
- Standard treatments offer a median progression-free survival of about 6.9 months. (2 links)
- Typically, tumors recur within 6 months of standard treatment. (2 links)
- Typically around 6-7 months for standard GBM treatments. (2 links)
- Under investigation; early results promising, especially in combination therapies (2 links)
- Variable across studies (2 links)
- Varied; one study showed median OS of 41.1 months with vaccine and temozolomide, and another indicated 30.3 months with vaccine and basiliximod. (2 links)