Category:Repurposed Drugs

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Repurposed Drugs

Repurposed drugs are medications originally developed and approved for one condition but researched for potential effectiveness in treating other diseases, including cancer. Unlike **off-label use**, which refers to prescribing an approved drug for an unapproved indication based on clinician discretion, **drug repurposing** involves systematic research into new applications, often supported by laboratory studies, clinical trials, or emerging scientific evidence. Repurposed drugs may offer new treatment avenues with established safety profiles, which can reduce the time and cost of bringing these therapies into clinical practice.

List of Repurposed Drugs

 Drug NameUsefulness Ratingtoxicity_level
AccutaneIsotretinoin (Accutane)33
CelebrexCelebrex (Celecoxib) and Other NSAIDs32.5
ChloroquineChloroquine and Hydroxychloroquine41
Chloroquine and HydroxychloroquineChloroquine and HydroxychloroquineNot ratedNot specified
DisulfiramDisulfiram (Antabuse)32
KeppraKeppra (Levetiracetam)42
LetrozoleLetrozole3 - Under investigation2.5
MN-166MN-166 (Ibudilast)3 (awaiting research)1
MetforminMetformin32
MethadoneMethadone (D,L-methadone)32
Proton Pump InhibitorsProton Pump Inhibitors (e.g., Lansoprazole, Nexium)32
TamoxifenTamoxifen33.5
ThalidomideThalidomide34
Trial of three drugs plus temodarCombination of Repurposed Drugs plus Temodar34
VT-122VT-122 (Propranolol and Etodolac combination)43
Valproic acidValproic Acid/Sodium Valproate (Depakote)33

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