User contributions for Lazy
From Glioblastoma Treatments
Jump to navigationJump to search
17 May 2024
- 09:0509:05, 17 May 2024 diff hist +356 Hyperthermia No edit summary current
- 09:0309:03, 17 May 2024 diff hist +1,629 N Hyperthermia Created page with "{{TreatmentInfo |drug_name=Hyperthermia |FDA_approval=Investigational |used_for=Glioblastoma Multiforme (GBM) |clinical_trial_phase=Phase I/II |common_side_effects=Localized discomfort, potential damage to surrounding healthy tissue |OS_without=Standard progression statistics for GBM |OS_with=Extended survival reported in some clinical trials |PFS_without=Standard progression statistics for GBM |PFS_with=Improved progression-free survival in combination with other treatm..."
15 May 2024
- 15:1015:10, 15 May 2024 diff hist −1 Main Page No edit summary
- 15:0915:09, 15 May 2024 diff hist +166 Main Page →Tumor-associated antigen vaccines
- 15:0215:02, 15 May 2024 diff hist +8 Chronotherapy No edit summary current
- 15:0115:01, 15 May 2024 diff hist +1,583 N Chronotherapy Created page with "{{TreatmentInfo |drug_name=Chronotherapy with Temozolomide (TMZ) |FDA_approval=Yes (as part of standard glioblastoma treatment) |used_for=Glioblastoma Multiforme (GBM) |clinical_trial_phase=Research ongoing |common_side_effects=Increased side effects when administered in the morning; however, these are generally manageable with other therapies. |OS_without=Around 19.5 months for patients with MGMT methylated tumors. |OS_with=Up to 17 months for general cases, and up to 2..."
28 April 2024
- 10:0110:01, 28 April 2024 diff hist −4 Main Page →Alternative Therapies Targeting GSCs
- 10:0010:00, 28 April 2024 diff hist −14 Main Page →Alternative Therapies Targeting GSCs
- 09:5709:57, 28 April 2024 diff hist +3,025 N Parthenolide Created page with "{{TreatmentInfo |drug_name=Parthenolide |FDA_approval=No (Used primarily in research settings; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment, specifically for its effects on glioblastoma and glioma stem cells |clinical_trial_phase=Preclinical studies |clinical_trial_explanation=Parthenolide is being studied for its potential anti-cancer properties in glioblastoma, particularly focusing on its ability to target and kill glioma st..." current
- 09:5509:55, 28 April 2024 diff hist −21 Metformin No edit summary current
- 09:5309:53, 28 April 2024 diff hist +2,886 N Metformin Created page with "{{TreatmentInfo |drug_name=Metformin |FDA_approval=Yes (Approved for type 2 diabetes; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment, specifically studied for effects on glioblastoma and glioma stem cells |clinical_trial_phase=Preclinical studies and some clinical trials |clinical_trial_explanation=Metformin is under investigation for its potential anti-cancer properties in glioblastoma, particularly its effects on glioma stem ce..."
- 09:4909:49, 28 April 2024 diff hist +27 Sulforaphane No edit summary current
- 09:4709:47, 28 April 2024 diff hist +2,892 N Sulforaphane Created page with "{{TreatmentInfo |drug_name=Sulforaphane |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment, particularly in preclinical studies focusing on glioblastoma |clinical_trial_phase=Preclinical studies |clinical_trial_explanation=Sulforaphane is being studied in preclinical models for its potential as an anti-cancer agent against glioblastoma. Research focuses on its ability to inhibit histone..."
- 09:4609:46, 28 April 2024 diff hist +3,405 N Resveratrol Created page with "{{TreatmentInfo |drug_name=Resveratrol |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment and prevention; also studied for cardiovascular benefits and anti-aging properties |clinical_trial_phase=Preclinical studies and early clinical trials |clinical_trial_explanation=Resveratrol is being studied for its potential anti-cancer properties in preclinical and early clinical trials, focusing..." current
- 09:4309:43, 28 April 2024 diff hist +2,257 Main Page →Cancer Stem Cells (CSCs) in Glioblastoma: Challenges with Standard of Care (SOC)
- 09:3709:37, 28 April 2024 diff hist +32 Main Page →Conclusion
- 09:3509:35, 28 April 2024 diff hist +79 Main Page →Conclusion
- 09:3309:33, 28 April 2024 diff hist +2,662 Main Page →The Standard of Care for Initial Treatment
- 09:2709:27, 28 April 2024 diff hist −3 MGMT →The role of MGMT current
12 April 2024
- 12:5512:55, 12 April 2024 diff hist +1,264 Curcumin No edit summary current
- 12:3212:32, 12 April 2024 diff hist +118 Template:TreatmentInfo No edit summary current
- 12:3112:31, 12 April 2024 diff hist +1 Melatonin No edit summary
- 12:3012:30, 12 April 2024 diff hist +621 Melatonin No edit summary
- 12:2312:23, 12 April 2024 diff hist +2,113 Melatonin No edit summary
5 April 2024
- 20:1920:19, 5 April 2024 diff hist +4,314 Vitamin D No edit summary current
- 20:1920:19, 5 April 2024 diff hist +5,039 Melatonin No edit summary
- 20:1920:19, 5 April 2024 diff hist +3,962 Thyroid Hormone T4 (Thyroxine) Suppression No edit summary current
- 20:1920:19, 5 April 2024 diff hist +5,763 N Beta-blockers (especially propranolol) and the role of the sympathetic Created page with " {{TreatmentInfo |drug_name=Beta-blockers (especially propranolol) and the role of the sympathetic |category=Hormones and Cancer Therapy |book_text=nervous system Recenty the role of the sympathetic nervous system in cancer progression, and the potential role of beta-adrenergic antagonists (beta-blockers) have come into focus in some corners of the cancer research community. Early studies linking stress to increased rates of cancer progression led to epidemiological st..." current
- 20:1920:19, 5 April 2024 diff hist +3,370 N Angiotensin-Il Receptor Blockers (ARB) Created page with " {{TreatmentInfo |drug_name=Angiotensin-Il Receptor Blockers (ARB) |category=Hormones and Cancer Therapy |book_text=Angiotensin-II is a peptide hormone produced from angiotensin-I by the action of angiotensin converting enzyme (ACE). The main effect of angiotensin-II is vasoconstriction and a resulting increase in blood pressure. Therefore ACE inhibitors and angiotensin-II receptor blockers are used as anti-hypertensive drugs, especially in heart disease. More recently..." current
- 20:1820:18, 5 April 2024 diff hist +1,525 N Herpes Virus Created page with " {{TreatmentInfo |drug_name=Herpes Virus |category=Oncolytic virotherapy |book_text=Another virus used in cancer therapy is a modified form of the herpes virus. Initial trials used a retrovirus version, which infects only those cells dividing when the virus was infused. Subsequent trials have used an adenovirus version, which infects both dividing and non-dividing cells. Because the herpes virus can be lethal to the brain if allowed to proliferate, soon after the virus..." current
- 20:1820:18, 5 April 2024 diff hist +581 N Newcastle Disease Virus Created page with " {{TreatmentInfo |drug_name=Newcastle Disease Virus |category=Oncolytic virotherapy |book_text=An alternative approach to vaccine treatment utilizes viruses. Newcastle disease is a lethal chicken disease, which is caused by a virus that is innocuous to humans, causing only transitory mild flu-like symptoms. It was developed as a cancer treatment in Hungary but has largely been ignored in this country until only recently. Newcastle Disease Virus is currently being utiliz..." current
- 20:1820:18, 5 April 2024 diff hist +824 N DNX-2401 adenovirus Created page with " {{TreatmentInfo |drug_name=DNX-2401 adenovirus |category=Oncolytic virotherapy |book_text=Another viral therapy in phase 1 has had impressive results, comparable to the PVS-RIPO trial. DNX-2401 is a modified adenovirus that is directly injected into the tumor. Preliminary results of a phase 1 trial at MD Anderson in Houston, Texas were presented at the November 2014 SNO conference in Miami. 37 recurrent high-grade glioma patients had been treated, with no adverse event..." current
- 20:1820:18, 5 April 2024 diff hist +916 N Genetically modified Poliovirus (PVS-RIPO) Created page with " {{TreatmentInfo |drug_name=Genetically modified Poliovirus (PVS-RIPO) |category=Oncolytic virotherapy |book_text=In 2015, this phase I trial for recurrent glioblastoma at Duke University received a boost in public interest when an episode of the television show 60 minutes was devoted to it. Most exceptionally, the first two patients treated in this study were complete responders. As of March 2015 (when the 60 minutes special aired) these two complete responders were st..." current
31 March 2024
- 14:4014:40, 31 March 2024 diff hist −21 Template:PropertyTableFormat No edit summary current
- 14:3914:39, 31 March 2024 diff hist −162 Main Page →Other Chemotherapy and Cancer Drugs
- 14:3814:38, 31 March 2024 diff hist −112 Main Page →Antibody-Drug Conjugates and other protein-drug conjugates
- 14:3814:38, 31 March 2024 diff hist −414 Main Page →Tumor-associated antigen vaccines
- 14:3714:37, 31 March 2024 diff hist −107 Main Page →Tumor-associated antigen vaccines
- 14:3514:35, 31 March 2024 diff hist −2 Template:PropertyTableFormat No edit summary Tag: Manual revert
- 14:3414:34, 31 March 2024 diff hist −10 Template:PropertyTableFormat No edit summary Tag: Reverted
- 14:3314:33, 31 March 2024 diff hist +2 Template:PropertyTableFormat No edit summary Tag: Reverted
- 14:3114:31, 31 March 2024 diff hist +10 Template:PropertyTableFormat No edit summary Tag: Reverted
- 14:3014:30, 31 March 2024 diff hist +172 Main Page No edit summary
- 14:2714:27, 31 March 2024 diff hist +84 Template:PropertyTableFormat No edit summary
- 14:2314:23, 31 March 2024 diff hist +456 Main Page No edit summary
- 14:1614:16, 31 March 2024 diff hist +44 ICT-107 No edit summary current
- 13:3213:32, 31 March 2024 diff hist +45 SL-701 No edit summary current
- 13:3113:31, 31 March 2024 diff hist +45 Anti-CMV Dendritic Cell Vaccine No edit summary current
- 13:3113:31, 31 March 2024 diff hist +44 Rindopepimut (CDX-110) No edit summary current
- 13:3013:30, 31 March 2024 diff hist +44 Wilms Tumor 1 (WT1) Peptide Vaccine No edit summary