Accutane: Difference between revisions
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|PFS_with=Not specified | |PFS_with=Not specified | ||
|usefulness_rating=3 | |usefulness_rating=3 | ||
|category=Repurposed | |category=Repurposed Drugs | ||
|notes=Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects. | |notes=Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects. | ||
|links=[St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html) | |links=[St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html) | ||
}} | }} | ||
Revision as of 13:36, 23 March 2024
| Property | Information |
|---|---|
| Drug Name | Isotretinoin (Accutane) |
| FDA Approval | Yes (for acne treatment) |
| Used for | Neuroblastoma, severe acne |
| Clinical Trial Phase | Used in various studies for cancer treatment |
| Clinical Trial Explanation | Not specified |
| Common Side Effects | Dry skin, liver problems, increased blood lipid levels, dry mouth, muscle or joint pain, sun sensitivity |
| OS without | Not specified |
| OS with | Not specified |
| PFS without | Not specified |
| PFS with | Not specified |
| Usefulness Rating | 3 |
| Usefulness Explanation | Not specified |
| Toxicity Level | Not specified |
| Toxicity Explanation | Not specified |
Notes: Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects.
Links: [St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html)
From Ben Williams Book: Not specified
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