Accutane: Difference between revisions

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(Created page with "{{TreatmentInfo |drug_name=Isotretinoin (Accutane) |FDA_approval=Yes (for acne treatment) |used_for=Neuroblastoma, severe acne |clinical_trial_phase=Used in various studies for cancer treatment |common_side_effects=Dry skin, liver problems, increased blood lipid levels, dry mouth, muscle or joint pain, sun sensitivity |OS_without=Not specified |OS_with=Not specified |PFS_without=Not specified |PFS_with=Not specified |usefulness_rating=3 |notes=Isotretinoin, a retinoid re...")
 
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|PFS_with=Not specified
|PFS_with=Not specified
|usefulness_rating=3
|usefulness_rating=3
|category=Repurposed drugs
|notes=Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects.
|notes=Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects.
|links=[St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html)
|links=[St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html)
}}
}}

Revision as of 14:35, 23 March 2024

Property Information
Drug Name Isotretinoin (Accutane)
FDA Approval Yes (for acne treatment)
Used for Neuroblastoma, severe acne
Clinical Trial Phase Used in various studies for cancer treatment
Clinical Trial Explanation Not specified
Common Side Effects Dry skin, liver problems, increased blood lipid levels, dry mouth, muscle or joint pain, sun sensitivity
OS without Not specified
OS with Not specified
PFS without Not specified
PFS with Not specified
Usefulness Rating 3
Usefulness Explanation Not specified
Toxicity Level Not specified
Toxicity Explanation Not specified

Notes: Isotretinoin, a retinoid related to vitamin A, controls cell growth by acting on specific nuclear receptors. It's used to treat severe acne and explored for cancer therapy potential, notably in neuroblastoma. It's important to avoid vitamin A supplements during treatment to prevent adverse interactions. Monitoring for liver function and blood lipid levels is advised due to possible side effects.

Links: [St. Jude’s comprehensive guide on isotretinoin](https://together.stjude.org/en-us/about-pediatric-cancer/treatment/medicines/isotretinoin.html)

From Ben Williams Book: Not specified

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