GLA: Difference between revisions

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(Created page with "{{TreatmentInfo |drug_name=Gamma-Linolenic Acid (GLA) |FDA_approval=No (Used as a dietary supplement) |used_for=Considered for cancer treatment support, but recommended to use omega-3 fatty acids from fish oil instead |clinical_trial_phase=Preclinical (rodent studies) |common_side_effects=Not specifically mentioned; dietary supplements like GLA are generally well-tolerated |OS_with=Not applicable; current recommendations favor omega-3 fatty acids for potential CNS benefi...")
 
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|toxicity_explanation=Gamma-Linolenic Acid (GLA) is a type of dietary supplement and not a specific cancer treatment. It's generally well-tolerated with no specific common side effects mentioned from its usage. However, it's not ideally recommended for treating glioblastoma as it does not effectively cross into the central nervous system or reach brain tumors after oral administration. Omega-3 fatty acids are recommended instead due to their higher potential of reaching the brain and they are also more cost-effective. The toxicity level of 1 signifies that it's considered low risk and unlikely to cause harmful effects.
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Revision as of 08:53, 27 March 2024

Property Information
Drug Name Gamma-Linolenic Acid (GLA)
FDA Approval No (Used as a dietary supplement)
Used for Considered for cancer treatment support, but recommended to use omega-3 fatty acids from fish oil instead
Clinical Trial Phase Preclinical (rodent studies)
Clinical Trial Explanation Not specified
Common Side Effects Not specifically mentioned; dietary supplements like GLA are generally well-tolerated
OS without Not specified
OS with Not applicable; current recommendations favor omega-3 fatty acids for potential CNS benefits
PFS without Not specified
PFS with Not applicable; emphasis on omega-3 fatty acids due to better CNS penetration and cost-effectiveness
Usefulness Rating 2
Usefulness Explanation Not specified
Toxicity Level 1
Toxicity Explanation Gamma-Linolenic Acid (GLA) is a type of dietary supplement and not a specific cancer treatment. It's generally well-tolerated with no specific common side effects mentioned from its usage. However, it's not ideally recommended for treating glioblastoma as it does not effectively cross into the central nervous system or reach brain tumors after oral administration. Omega-3 fatty acids are recommended instead due to their higher potential of reaching the brain and they are also more cost-effective. The toxicity level of 1 signifies that it's considered low risk and unlikely to cause harmful effects.

Notes: Despite the potential of GLA as a dietary supplement, rodent studies indicate it does not effectively cross into the central nervous system or reach brain tumors after oral administration. Omega-3 fatty acids such as EPA and DHA, which are detectable in human cerebrospinal fluid and more likely to enter the CNS, are recommended instead. Omega-3s are also more cost-effective and share similar mechanisms of action to GLA.


From Ben Williams Book: Not specified

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