While TMZ is generally well-tolerated, it can cause side effects such as nausea, vomiting, and hematological toxicities like neutropenia and thrombocytopenia. These side effects are typically manageable with supportive care.
[2,"smw-datavalue-wikipage-property-invalid-title","Has Usefulness Explanation","Temozolomide is the standard chemotherapy for GBM and has been shown to extend survival when used in combination with radiotherapy. While not curative, it provides a significant survival benefit, particularly for patients with MGMT methylation. Its oral administration makes it more convenient than intravenous chemotherapies, and its side effects are generally manageable. However, its effectiveness is limited in patients with unmethylated MGMT, and resistance often develops over time."]
Temozolomide# ERR0de0b09fdf871942cb9b8a10a8978dce