]> 2026-04-12T04:07:18-07:00 Platinum Compounds 0 en The treatment with Platinum Compounds (Cisplatin) is considered relatively high in toxicity due to potential side effects like kidney damage (Nephrotoxicity), hearing loss (ototoxicity), and nervous system damage (neurotoxicity). It's important for patients to discuss these risks with their healthcare provider before starting therapy. A toxicity level of 4 out of 5 means this treatment carries significant risks, but it may be necessary for managing glioblastoma. 2025-01-18T08:22:18Z 2460693.8488194 Platinum Compounds 0 [2,"smw-datavalue-wikipage-property-invalid-title","Has original text","An improvement in results relative to those obtained with Temodar alone has also been\nreported when Temodar has been combined with cisplatin. In a pair of clinical studies\nperformed in Italy (61, 62) with patients with recurrent tumors, the PFS-6 was 34% and\n35%. A treatment protocol with newly diagnosed patients that also seems to have\nproduced better results than Temodar as a single agent combined Temodar with both\ncisplatin and etoposide (VP-16), given through the carotid artery (63). Cisplatin and\netoposide were given after surgery and continued for three cycles spaced every 3 weeks\napart, followed by the standard protocol of radiation plus low-dose Temodar, then\nhigh-dose Temodar on the schedule of days 1-5 of every month. For 15 patients studied,\nmedian survival was 25 months."] Platinum Compounds# ERRa3f62c6665776505f0db7c26c19aebf1 Has treatment name 102 en Has treatment name