]> 2026-04-12T05:41:01-07:00 Herpes Virus 0 en Not specified 2025-01-18T08:29:37Z 2460693.8539005 Herpes Virus 0 [2,"smw-datavalue-wikipage-property-invalid-title","Has original text","Another virus used in cancer therapy is a modified form of the herpes virus. Initial trials\nused a retrovirus version, which infects only those cells dividing when the virus was\ninfused. Subsequent trials have used an adenovirus version, which infects both dividing\nand non-dividing cells. Because the herpes virus can be lethal to the brain if allowed to\nproliferate, soon after the virus infusion patients receive ganciclovir, an effective\nanti-herpes agent. In one study using this technique performed at Mt. Sinai Hospital in\nNew York (170), median survival of 12 patients with recurrent GBM tumors was 59 weeks\nfrom the point of treatment, with 50% of the patients alive 12 months after the treatment.\nThe authors also reported the absence of toxicity from the treatment, which was a major\nconcern due to significant brain damage when the procedure was tested with monkeys.\nWhy the difference from the monkey study's results is unclear.\n\nMore recent research with the herpes virus has been focused on forms of the virus that\nhave been engineered to retain the anti-cancer effects of the virus but without its property\nof producing neurological inflammation. The first use of this modified virus in a clinical\ntrial was in Glasgow, Scotland. Nine patients with recurrent glioblastomas received the\nvirus injected directly into the tumor. Four were alive at the time of the report of the\nstudy, 14-24 months after the treatment (171)."] Herpes Virus# ERRa3f62c6665776505f0db7c26c19aebf1 Has treatment name 102 en Has treatment name