Category:RepurposedDrugs

There are a large number of drugs that were developed initially for various different purposes that subsequent laboratory research demonstrated to have significant anti-cancer properties. Given these old drugs have been used for years, have well-defined toxicity profiles, and are generally cheaper due to being off-patent, they offer the possibility of augmenting the benefits of the current standard treatment without significant additional toxicity. However, because their FDA approval is for different purposes, many if not most neuro-oncologists have been reluctant to take advantage of their possible benefits as components of a treatment cocktail. Some of these drugs have been investigated as single agents for brain cancer treatment and some have also been combined with the now standard Stupp protocol.