All public logs

Combined display of all available logs of Glioblastoma Treatments. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

• 08:48, 19 March 2024 Lazy talk contribs created page Tamoxifen (Created page with "{{TreatmentInfo |drug_name=Tamoxifen |FDA_approval=Yes (for breast cancer treatment) |used_for=Investigational use in glioblastoma (GBM) treatment |clinical_trial_phase=Phase II clinical trials and retrospective studies |common_side_effects=Increased risk of blood clots, uterine cancer in women, impotence, and loss of libido in men, weight gain |OS_without=Not specified |OS_with=Varies; in gliomas, doses range from 160-240 mg per day showed tumor regression in 25% of pat...")
• 08:45, 19 March 2024 Lazy talk contribs created page Proton Pump Inhibitors (Created page with "{{TreatmentInfo |drug_name=Proton Pump Inhibitors (e.g., Lansoprazole, Nexium) |FDA_approval=Yes (for heartburn and acid-related issues) |used_for=Investigational use in enhancing sensitivity of cancer cells to chemotherapy |clinical_trial_phase=Preclinical studies and observational studies in animals and humans |common_side_effects=Common PPI side effects include headache, nausea, diarrhea, abdominal pain, fatigue, and dizziness |OS_without=Not specified |OS_with=Studie...")
• 08:41, 19 March 2024 Lazy talk contribs created page Methadone (Created page with "{{TreatmentInfo |drug_name=Methadone (D,L-methadone) |FDA_approval=Yes (for pain management and replacement therapy for addiction) |used_for=Investigational use in glioblastoma treatment for its chemosensitizing effects |clinical_trial_phase=Preclinical studies and a retrospective safety and tolerability study in glioma patients |common_side_effects=Nausea, constipation (obstipation); side effects commonly resolved after one month of therapy |OS_without=Not specified in...")
• 08:35, 19 March 2024 Lazy talk contribs created page Keppra (Created page with "{{TreatmentInfo |drug_name=Keppra (Levetiracetam) |FDA_approval=Yes (as an anti-seizure medication, 1999) |used_for=Seizure prevention in brain tumor patients, potential sensitizer for glioblastoma cells to temozolomide chemotherapy |clinical_trial_phase=Retrospective studies and laboratory research |common_side_effects=Common side effects associated with Keppra include fatigue, dizziness, and mood changes, but it is generally well-tolerated in the context of brain tumor...")
• 08:32, 19 March 2024 Lazy talk contribs created page Disulfiram (Created page with "{{TreatmentInfo |drug_name=Disulfiram (Antabuse) |FDA_approval=Yes (for preventing alcohol consumption) |used_for=Exploratory treatment for GBM in combination with temozolomide and potentially copper gluconate |clinical_trial_phase=Phase I pharmacodynamics trial at Washington University, ongoing research |common_side_effects=At higher doses: delirium and peripheral motor neuropathy; minimal toxicity when alcohol is not consumed |OS_without=Not specified |OS_with=Early re...")
• 08:23, 19 March 2024 Lazy talk contribs created page Chloroquine (Created page with "{{TreatmentInfo |drug_name=Chloroquine and Hydroxychloroquine |FDA_approval=No (for glioblastoma treatment) |used_for=Glioblastoma, in combination with traditional chemotherapy agents |clinical_trial_phase=Reviewed in recent meta-analyses and studies |common_side_effects=Generally well-tolerated; specific studies noted minimal impact on adverse event incidence |OS_without=BCNU alone: median survival of 11 months |OS_with=Chloroquine with BCNU: median survival significant...")
• 07:40, 19 March 2024 Lazy talk contribs created page Accutane (Created page with "{{TreatmentInfo |drug_name=Isotretinoin (Accutane) |FDA_approval=Yes (for acne treatment) |used_for=Neuroblastoma, severe acne |clinical_trial_phase=Used in various studies for cancer treatment |common_side_effects=Dry skin, liver problems, increased blood lipid levels, dry mouth, muscle or joint pain, sun sensitivity |OS_without=Not specified |OS_with=Not specified |PFS_without=Not specified |PFS_with=Not specified |usefulness_rating=3 |notes=Isotretinoin, a retinoid re...")
• 07:34, 19 March 2024 Lazy talk contribs created page Vitamin D (Created page with "{{TreatmentInfo |drug_name=Vitamin D (Alfacalcidol, Paricalcitol, Cholecalciferol variants) |FDA_approval=No |used_for=Glioblastoma Multiforme (GBM), various types of cancer |clinical_trial_phase=Various studies, including recent meta-analyses and reviews |common_side_effects=Hypercalcemia at high doses of calcitriol; other forms generally safe |OS_without=Not explicitly detailed in recent reviews |OS_with=Recent meta-analyses suggest potential for improving cancer treat...")
• 07:21, 19 March 2024 Lazy talk contribs created page Melatonin (Created page with "{{TreatmentInfo |drug_name=Melatonin |FDA_approval=No |used_for=Glioblastoma Multiforme (GBM), insomnia, jet lag |clinical_trial_phase=Mixed (Phase 2 and Phase 3 trials mentioned) |common_side_effects=No known toxic side effects |OS_without=Survival significantly greater in melatonin-treated subjects in small GBM study |OS_with=Increases efficacy of chemotherapy; significant survival benefit observed in various cancers |PFS_without=Not specified |PFS_with=Not specified |...")
• 21:43, 17 March 2024 Lazy talk contribs created page Form:TreatmentInfo (Created page with "<noinclude> This is the "TreatmentInfo" form. To create a page with this form, enter the page name below; if a page with that name already exists, you will be sent to a form to edit that page. {{#forminput:form=TreatmentInfo}} </noinclude><includeonly> <div id="wikiPreview" style="display: none; padding-bottom: 25px; margin-bottom: 25px; border-bottom: 1px solid #AAAAAA;"></div> {{{for template|TreatmentInfo}}} {| class="formtable" ! !: | {{{field|!}}} |- ! Drug_name:...")
• 21:06, 17 March 2024 Lazy talk contribs created page Berberine (Created page with "{{TreatmentInfo |drug_name=Berberine |FDA_approval=No |used_for=Glioblastoma Multiforme (GBM) |OS_without=Not explicitly mentioned; refer to specific studies for detailed metrics. |OS_with=Studies suggest enhancement of temozolomide efficacy in resistant GBM cases, potentially improving overall survival rates. |clinical_trial_phase=Pre-clinical (in vitro and in vivo studies) |common_side_effects=Not specifically listed for GBM treatment; generally well-tolerated but can...")
• 21:03, 17 March 2024 Lazy talk contribs created page Category:Nutraceuticals (Created page with "= Nutraceuticals and Herbals = Oncologists routinely warn their patients not to use supplements, usually based on the belief that supplements that are anti-oxidants will interfere with both radiation and chemotherapy. While this issue is extremely complex, my own evaluation of the relevant evidence strongly disagrees with this opinion. [Introduction continues...] == List of Nutraceutical Treatments == {{#ask: Category:Nutraceuticals |?Has treatment name |?Has OS w...")
• 19:50, 17 March 2024 Lazy talk contribs created page Cimetidine (Created page with "{{TreatmentInfo |drug_name=Cimetidine (Tagamet) |FDA_approval=Yes (for stomach conditions, not specifically approved for brain cancer yet) |used_for=Experimental for glioblastoma; approved for stomach acid reduction; noted use in colon cancer |mechanism_of_action=Decreases cell migration by affecting genes controlling cellular adhesion |clinical_trial_year=Recent (specific year not mentioned) |number_of_patients=N/A (mouse study) |median_survival=Substantially longer sur...")
• 08:54, 16 March 2024 Lazy talk contribs created page Clomipramine (Created page with "{{TreatmentInfo |drug_name=Clomipramine |FDA_approval=Yes |used_for=Depression, Obsessive-compulsive disorder, GBM |category=Repurposed Drugs }}")
• 08:45, 16 March 2024 Lazy talk contribs created page Category:RepurposedDrugs (Created page with "There are a large number of drugs that were developed initially for various different purposes that subsequent laboratory research demonstrated to have significant anti-cancer properties. Given these old drugs have been used for years, have well-defined toxicity profiles, and are generally cheaper due to being off-patent, they offer the possibility of augmenting the benefits of the current standard treatment without significant additional toxicity. However, because their...")
• 08:44, 16 March 2024 Lazy talk contribs created page Category:Hormones (Created page with "Unlike traditional cancer chemotherapy, which kills cancer cells through directly cytotoxic mechanisms, a different approach may also prove to be effective: manipulation of the body’s balance of circulating hormones to achieve the most unwelcoming environment for the growth of tumors.")
• 08:44, 16 March 2024 Lazy talk contribs created page Template:TreatmentInfo (Created page with "<noinclude> This template is for adding treatments. <includeonly> {| class="wikitable" |- ! Property !! Information |- | Drug Name || [[Has treatment name::{{{drug_name|}}}]] |- | FDA Approval || [[Is FDA approved::{{{FDA_approval|}}}]] |- | Used for || [[Used for condition::{{{used_for|}}}]] |- ... |} [[Category:{{{category|}}}]] </includeonly> </noinclude>")