Wanted pages
From Glioblastoma Treatments
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List of non-existing pages with the most links to them, excluding pages which only have redirects linking to them. For a list of non-existent pages that have redirects linking to them, see the list of broken redirects.
Showing below up to 50 results in range #101 to #150.
- Pending further clinical trials (2 links)
- Pending further clinical trials and data (2 links)
- Pending review of recent clinical trials and comparative studies (2 links)
- Phase 3 (2 links)
- Phase III (2 links)
- Phase III ACT IV trial did not show a significant increase in OS; however, a Phase II trial (ReACT) in recurrent GBM showed improved outcomes with bevacizumab (2 links)
- Phase II trial showed a significant improvement in PFS, particularly for HLA-A2 positive patients with methylated MGMT, showing a median PFS of 24.1 months vs. 8.5 months in the control group. (2 links)
- Post-hoc analysis with at least six months of Valcyte use: median survival of 24 months, 4-year survival of 27% (2 links)
- Preclinical studies (2 links)
- Preclinical studies and early clinical trials (2 links)
- Proton Pump Inhibitors (e.g., Lansoprazole, Nexium) (2 links)
- Radiation dermatitis, temporary alopecia, radiation otitis, radiation necrosis (more prevalent in PBT group) (2 links)
- Ranges from 26 to 44% with different schedules; 61% PFS-6 with the best results obtained using a specific dosing schedule (2 links)
- ReACT trial showed a 6-month PFS of 28% for the rindopepimut group compared to 16% for the control (2 links)
- Recent meta-analyses suggest potential for improving cancer treatment outcomes (2 links)
- SL-701 (Immunotherapy Vaccine) (2 links)
- Shows a clinically meaningful extension of survival in both newly diagnosed and recurrent GBM patients. Offers fresh hope by potentially improving outcomes in a challenging treatment landscape. (2 links)
- Shows promise based on significant improvements in overall survival and disease-free survival in high-risk AML patients; ongoing research needed to fully establish efficacy in other cancers (2 links)
- Some studies report mean progression-free survival up to 17.2 months, compared to 4-10 months for other treatments (2 links)
- Stage 1 median overall survival was 11.0 months with a 12-month OS rate of 44%. Stage 2 showed a median OS of 11.7 months with a 12-month OS rate of 50%, suggesting an improvement over historical data. (2 links)
- Standard radiation therapy PFS rates are lower compared to PBT (2 links)
- Standard treatments for GBM typically result in a median overall survival of 14-17 months (2 links)
- Standard treatments offer a median PFS of about 6.9 months (2 links)
- Standard treatments offer a median progression-free survival of about 6.9 months. (2 links)
- The 2021 trial reported an increase in overall survival for glioblastoma patients treated with Sativex in combination with temozolomide compared to temozolomide alone (2 links)
- The vaccine shows promise, especially in extending progression-free survival in newly diagnosed GBM. It offers a novel approach by leveraging the patient's immune system, potentially improving outcomes in a disease with few effective treatments. (2 links)
- Typically, tumors recur within 6 months of standard treatment. (2 links)
- Typically around 6-7 months for standard GBM treatments. (2 links)
- Under investigation; early results promising, especially in combination therapies (2 links)
- Valganciclovir (Valcyte) (2 links)
- Valproic Acid/Sodium Valproate (Depakote) (2 links)
- Variable across studies (2 links)
- Varied; one study showed median OS of 41.1 months with vaccine and temozolomide, and another indicated 30.3 months with vaccine and basiliximod. (2 links)
- Varies; can include fatigue, headache, localized reactions at infusion site (2 links)
- Varies; earlier phases showed median overall survival up to 38 months in phase I trial participants. (2 links)
- While initial phase III trial results in newly diagnosed GBM were disappointing, the ReACT trial for recurrent GBM suggests potential benefits, particularly when combined with bevacizumab (2 links)
- Wilms Tumor Peptide Vaccine (2 links)
- Property:Has Usefulness Explanation (2 links)
- 13.5 months for general cases, 19.5 months for patients with MGMT methylated tumors. (1 link)
- 17.8 months for newly diagnosed GBM, possibly the longest PFS seen in a phase II trial for GBM (1 link)
- 17 months for general cases, 25.5 months for patients with MGMT methylated tumors when administered in the morning. (1 link)
- 4 months (control group in EF-14 Trial) (1 link)
- 7.1 months (Optune arm in EF-14 Trial); 6.7 months from diagnosis in updated analysis (1 link)
- 7.5 months in metastatic breast cancer patients receiving only chemotherapy (1 link)
- 9.5 months with 100 mg Nexium; 10.9 months with 80 mg Nexium (1 link)
- At higher doses: delirium and peripheral motor neuropathy; minimal toxicity when alcohol is not consumed (1 link)
- BCNU alone: median survival of 11 months (1 link)
- Blood clots, increased risk of uterine cancer in women, impotence and loss of libido in men, weight gain (1 link)
- Carefully monitored to avoid clinical symptoms of hypothyroidism; includes potential for fatigue if not properly managed (1 link)
- Chloroquine with BCNU: median survival significantly improved to 25-33 months; recent meta-analysis supports decreased mortality and improved survival time in glioblastoma patients (1 link)