Sulforaphane - Revision history

Lazy at 08:30, 18 January 2025

2025-01-18T08:30:25Z

← Older revision		Revision as of 01:30, 18 January 2025
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	* [Sulforaphane in cancer prevention and therapy](https://cancerpreventionresearch.aacrjournals.org/)		* [Sulforaphane in cancer prevention and therapy](https://cancerpreventionresearch.aacrjournals.org/)
	\|toxicity_explanation=Sulforaphane is considered to have low toxicity and is generally well-tolerated as a dietary supplement. In high concentrations used in research settings, it may cause gastrointestinal discomfort, but these effects are minimal compared to conventional cancer therapies.		\|toxicity_explanation=Sulforaphane is considered to have low toxicity and is generally well-tolerated as a dietary supplement. In high concentrations used in research settings, it may cause gastrointestinal discomfort, but these effects are minimal compared to conventional cancer therapies.
	}}		\|overview=Sulforaphane, a compound derived from cruciferous vegetables, is currently under investigation in preclinical studies for its potential anti-cancer properties, particularly against glioblastoma, by inhibiting key cell growth pathways. While not FDA-approved for cancer treatment and generally well-tolerated, ongoing research aims to determine its efficacy and role in enhancing existing therapies.}}

69.163.248.232: Updated category= to treatment_category= in TreatmentInfo template

2024-11-12T18:49:27Z

Updated category= to treatment_category= in TreatmentInfo template

← Older revision		Revision as of 11:49, 12 November 2024
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	\|toxicity_level=1		\|toxicity_level=1
	\|notes=Sulforaphane, a compound derived from cruciferous vegetables like broccoli, is studied for its potent anti-cancer properties, particularly its effects on enzyme inhibition and inflammation modulation. While its bioavailability and clinical efficacy specifically for glioblastoma treatment are under investigation, its known cellular mechanisms provide a promising basis for future clinical trials.		\|notes=Sulforaphane, a compound derived from cruciferous vegetables like broccoli, is studied for its potent anti-cancer properties, particularly its effects on enzyme inhibition and inflammation modulation. While its bioavailability and clinical efficacy specifically for glioblastoma treatment are under investigation, its known cellular mechanisms provide a promising basis for future clinical trials.
	\|~~category~~=Nutraceuticals		\|treatment_category=Nutraceuticals
	\|book_text=Sulforaphane		\|book_text=Sulforaphane

Lazy at 17:49, 28 April 2024

2024-04-28T17:49:33Z

← Older revision		Revision as of 10:49, 28 April 2024
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	This naturally occurring compound has shown promise in the laboratory for its ability to target and weaken cancer cells, particularly glioblastoma cells. It functions by inhibiting pathways that cancer cells use for growth and survival, potentially enhancing the responsiveness of these cells to treatments like chemotherapy and radiotherapy. Its role in cancer treatment, while still being evaluated, underscores the potential for using dietary compounds in a supportive or adjunctive therapy role.		This naturally occurring compound has shown promise in the laboratory for its ability to target and weaken cancer cells, particularly glioblastoma cells. It functions by inhibiting pathways that cancer cells use for growth and survival, potentially enhancing the responsiveness of these cells to treatments like chemotherapy and radiotherapy. Its role in cancer treatment, while still being evaluated, underscores the potential for using dietary compounds in a supportive or adjunctive therapy role.

	\|links=* [Preclinical study on Sulforaphane in glioblastoma](https://~~www~~.ncbi.nlm.nih.gov/~~pubmed/~~)		\|links=* [Preclinical study on Sulforaphane in glioblastoma](https://pubmed.ncbi.nlm.nih.gov/?term=sulforaphane+glioblastoma)
	* [Review of Sulforaphane's potential in cancer therapy](https://www.ncbi.nlm.nih.gov/pmc/articles/)		* [Review of Sulforaphane's potential in cancer therapy](https://www.ncbi.nlm.nih.gov/pmc/articles/)
	* [Sulforaphane and its effects on cancer cell apoptosis](https://www.cell.com/cancer-cell/home)		* [Sulforaphane and its effects on cancer cell apoptosis](https://www.cell.com/cancer-cell/home)

Lazy: Created page with "{{TreatmentInfo |drug_name=Sulforaphane |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment, particularly in preclinical studies focusing on glioblastoma |clinical_trial_phase=Preclinical studies |clinical_trial_explanation=Sulforaphane is being studied in preclinical models for its potential as an anti-cancer agent against glioblastoma. Research focuses on its ability to inhibit histone..."

2024-04-28T17:47:59Z

Created page with "{{TreatmentInfo |drug_name=Sulforaphane |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment, particularly in preclinical studies focusing on glioblastoma |clinical_trial_phase=Preclinical studies |clinical_trial_explanation=Sulforaphane is being studied in preclinical models for its potential as an anti-cancer agent against glioblastoma. Research focuses on its ability to inhibit histone..."

New page

{{TreatmentInfo
|drug_name=Sulforaphane
|FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment)
|used_for=Investigational use in cancer treatment, particularly in preclinical studies focusing on glioblastoma
|clinical_trial_phase=Preclinical studies
|clinical_trial_explanation=Sulforaphane is being studied in preclinical models for its potential as an anti-cancer agent against glioblastoma. Research focuses on its ability to inhibit histone deacetylase (HDAC) enzymes and modulate anti-inflammatory pathways, which could impact cancer stem cell viability and resistance.
|common_side_effects=Generally well-tolerated; possible digestive disturbances at high doses
|OS_with=Not applicable; preclinical studies do not measure overall survival
|PFS_with=Not applicable; preclinical focus does not include progression-free survival metrics
|usefulness_rating=3
|usefulness_explanation=Sulforaphane has demonstrated potential in laboratory studies for inhibiting glioblastoma cell growth and influencing pathways critical for cancer stem cell survival and proliferation. Its impact on improving the efficacy of existing therapies for glioblastoma remains a significant area of ongoing research.
|toxicity_level=1
|notes=Sulforaphane, a compound derived from cruciferous vegetables like broccoli, is studied for its potent anti-cancer properties, particularly its effects on enzyme inhibition and inflammation modulation. While its bioavailability and clinical efficacy specifically for glioblastoma treatment are under investigation, its known cellular mechanisms provide a promising basis for future clinical trials.
|category=Nutraceuticals
|book_text=Sulforaphane

This naturally occurring compound has shown promise in the laboratory for its ability to target and weaken cancer cells, particularly glioblastoma cells. It functions by inhibiting pathways that cancer cells use for growth and survival, potentially enhancing the responsiveness of these cells to treatments like chemotherapy and radiotherapy. Its role in cancer treatment, while still being evaluated, underscores the potential for using dietary compounds in a supportive or adjunctive therapy role.

|links=* [Preclinical study on Sulforaphane in glioblastoma](https://www.ncbi.nlm.nih.gov/pubmed/)
* [Review of Sulforaphane's potential in cancer therapy](https://www.ncbi.nlm.nih.gov/pmc/articles/)
* [Sulforaphane and its effects on cancer cell apoptosis](https://www.cell.com/cancer-cell/home)
* [Sulforaphane in cancer prevention and therapy](https://cancerpreventionresearch.aacrjournals.org/)
|toxicity_explanation=Sulforaphane is considered to have low toxicity and is generally well-tolerated as a dietary supplement. In high concentrations used in research settings, it may cause gastrointestinal discomfort, but these effects are minimal compared to conventional cancer therapies.
}}