Resveratrol - Revision history

Lazy at 08:30, 18 January 2025

2025-01-18T08:30:06Z

← Older revision		Revision as of 01:30, 18 January 2025
Line 23:		Line 23:
	* [Resveratrol—Challenges in Translation to the Clinic—A Critical Discussion](https://www.mdpi.com/1422-0067/11/12/4745)		* [Resveratrol—Challenges in Translation to the Clinic—A Critical Discussion](https://www.mdpi.com/1422-0067/11/12/4745)
	\|toxicity_explanation=Resveratrol is generally well-tolerated with minimal side effects reported at dietary supplement levels. Higher doses used in clinical trials have occasionally resulted in gastrointestinal issues, but overall, it carries a low toxicity profile. As a dietary supplement, it has minimal regulatory oversight but is extensively studied for its broad pharmacological effects.		\|toxicity_explanation=Resveratrol is generally well-tolerated with minimal side effects reported at dietary supplement levels. Higher doses used in clinical trials have occasionally resulted in gastrointestinal issues, but overall, it carries a low toxicity profile. As a dietary supplement, it has minimal regulatory oversight but is extensively studied for its broad pharmacological effects.
	}}		\|overview=Resveratrol, a dietary supplement not FDA-approved for cancer treatment, is being investigated for its potential anti-cancer properties, particularly in hormone-sensitive cancers, alongside its cardiovascular and anti-aging benefits. While it is generally well-tolerated, further research is needed to validate its effectiveness and optimize its clinical applications.}}

69.163.248.232: Updated category= to treatment_category= in TreatmentInfo template

2024-11-12T18:49:00Z

Updated category= to treatment_category= in TreatmentInfo template

← Older revision		Revision as of 11:49, 12 November 2024
Line 12:		Line 12:
	\|toxicity_level=1		\|toxicity_level=1
	\|notes=Resveratrol, found in the skin of grapes and berries, exhibits properties that may inhibit cancer development and progression. It has been noted for its anti-inflammatory and antioxidant effects, which could play a role in its anti-cancer activities. While it has shown promise in laboratory studies, further research is necessary to establish its effectiveness and optimal use in clinical settings.		\|notes=Resveratrol, found in the skin of grapes and berries, exhibits properties that may inhibit cancer development and progression. It has been noted for its anti-inflammatory and antioxidant effects, which could play a role in its anti-cancer activities. While it has shown promise in laboratory studies, further research is necessary to establish its effectiveness and optimal use in clinical settings.
	\|~~category~~=Nutraceuticals		\|treatment_category=Nutraceuticals
	\|book_text=Resveratrol		\|book_text=Resveratrol

Lazy: Created page with "{{TreatmentInfo |drug_name=Resveratrol |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment and prevention; also studied for cardiovascular benefits and anti-aging properties |clinical_trial_phase=Preclinical studies and early clinical trials |clinical_trial_explanation=Resveratrol is being studied for its potential anti-cancer properties in preclinical and early clinical trials, focusing..."

2024-04-28T17:46:06Z

Created page with "{{TreatmentInfo |drug_name=Resveratrol |FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment) |used_for=Investigational use in cancer treatment and prevention; also studied for cardiovascular benefits and anti-aging properties |clinical_trial_phase=Preclinical studies and early clinical trials |clinical_trial_explanation=Resveratrol is being studied for its potential anti-cancer properties in preclinical and early clinical trials, focusing..."

New page

{{TreatmentInfo
|drug_name=Resveratrol
|FDA_approval=No (Used as a dietary supplement; not FDA-approved for cancer treatment)
|used_for=Investigational use in cancer treatment and prevention; also studied for cardiovascular benefits and anti-aging properties
|clinical_trial_phase=Preclinical studies and early clinical trials
|clinical_trial_explanation=Resveratrol is being studied for its potential anti-cancer properties in preclinical and early clinical trials, focusing on its ability to modulate various signaling pathways involved in cell proliferation and survival.
|common_side_effects=Generally well-tolerated; some reports of gastrointestinal disturbances at high doses
|OS_with=Not applicable; studies focus on biomolecular impacts rather than direct survival outcomes
|PFS_with=Not applicable; research has not extensively measured progression-free survival in cancer patients
|usefulness_rating=3
|usefulness_explanation=Resveratrol has shown potential in laboratory studies for modulating pathways that influence cancer cell growth and apoptosis, particularly in hormone-sensitive cancers. Its role in enhancing the efficacy of existing cancer therapies and in chemoprevention is currently under investigation.
|toxicity_level=1
|notes=Resveratrol, found in the skin of grapes and berries, exhibits properties that may inhibit cancer development and progression. It has been noted for its anti-inflammatory and antioxidant effects, which could play a role in its anti-cancer activities. While it has shown promise in laboratory studies, further research is necessary to establish its effectiveness and optimal use in clinical settings.
|category=Nutraceuticals
|book_text=Resveratrol

This compound, commonly associated with red wine, has gained attention for its health benefits, including potential anti-cancer properties. It affects mechanisms like the inhibition of NF-kB and the activation of sirtuins that contribute to its anti-aging and anti-inflammatory effects. Although promising, its clinical efficacy in cancer treatment requires further validation.

Resveratrol's anti-cancer potential was highlighted in several studies where it was shown to modulate hormone receptor signaling pathways, making it of interest in hormone-driven cancers such as breast and prostate cancer. Like many supplements, its bioavailability is a concern, but ongoing research is addressing these challenges with novel delivery systems.
|links=* [ClinicalTrials.gov study on Resveratrol for various health outcomes](https://clinicaltrials.gov/ct2/results?cond=&term=resveratrol&cntry=&state=&city=&dist=)
* [Systematic review of the pharmacological effects of resveratrol in cancer and other diseases](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164842/)
* [Resveratrol and Cancer: Focus on in vivo evidence](https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00062-0)
* [Resveratrol—Challenges in Translation to the Clinic—A Critical Discussion](https://www.mdpi.com/1422-0067/11/12/4745)
|toxicity_explanation=Resveratrol is generally well-tolerated with minimal side effects reported at dietary supplement levels. Higher doses used in clinical trials have occasionally resulted in gastrointestinal issues, but overall, it carries a low toxicity profile. As a dietary supplement, it has minimal regulatory oversight but is extensively studied for its broad pharmacological effects.
}}