Limonene - Revision history

Lazy at 08:18, 18 January 2025

2025-01-18T08:18:36Z

← Older revision		Revision as of 01:18, 18 January 2025
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	\|toxicity_level=2		\|toxicity_level=2
	\|toxicity_explanation=Perillyl Alcohol and Limonene, despite being under investigation for anti-cancer properties, are derived from citrus oils and generally are not associated with severe toxic effects. They do result in some gastro-intestinal side effects when administered orally, but these side effects are mitigated by intranasal administration. However, as with any treatment, individual responses may vary.		\|toxicity_explanation=Perillyl Alcohol and Limonene, despite being under investigation for anti-cancer properties, are derived from citrus oils and generally are not associated with severe toxic effects. They do result in some gastro-intestinal side effects when administered orally, but these side effects are mitigated by intranasal administration. However, as with any treatment, individual responses may vary.
	}}		\|overview=Perillyl Alcohol and Limonene, currently under investigation for their anti-cancer properties, are being explored in early-stage clinical trials for recurrent glioma treatment, particularly through intranasal administration to reduce gastro-intestinal side effects. While not FDA approved, initial findings suggest potential effectiveness in prolonging survival, with median survival rates of 5.9 months for primary GBM and 11.2 months for secondary GBM.}}

69.163.248.232: Updated category= to treatment_category= in TreatmentInfo template

2024-11-12T18:27:04Z

Updated category= to treatment_category= in TreatmentInfo template

← Older revision		Revision as of 11:27, 12 November 2024
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	\|usefulness_rating=3		\|usefulness_rating=3
	\|notes=Perillyl Alcohol and Limonene, derived from citrus oils, have shown potential as anti-cancer agents. Clinical trials have explored their efficacy, particularly through intranasal administration to avoid gastro-intestinal side effects. Early findings suggest a degree of effectiveness in stabilizing disease and extending survival in recurrent GBM patients, with noted variance based on tumor type and location. Further research is needed to fully understand their therapeutic potential and optimal administration method.		\|notes=Perillyl Alcohol and Limonene, derived from citrus oils, have shown potential as anti-cancer agents. Clinical trials have explored their efficacy, particularly through intranasal administration to avoid gastro-intestinal side effects. Early findings suggest a degree of effectiveness in stabilizing disease and extending survival in recurrent GBM patients, with noted variance based on tumor type and location. Further research is needed to fully understand their therapeutic potential and optimal administration method.
	\|~~category~~=Over-the-Counter Drugs and Supplements		\|treatment_category=Over-the-Counter Drugs and Supplements
	\|links=		\|links=
	\|toxicity_level=2		\|toxicity_level=2
	\|toxicity_explanation=Perillyl Alcohol and Limonene, despite being under investigation for anti-cancer properties, are derived from citrus oils and generally are not associated with severe toxic effects. They do result in some gastro-intestinal side effects when administered orally, but these side effects are mitigated by intranasal administration. However, as with any treatment, individual responses may vary.		\|toxicity_explanation=Perillyl Alcohol and Limonene, despite being under investigation for anti-cancer properties, are derived from citrus oils and generally are not associated with severe toxic effects. They do result in some gastro-intestinal side effects when administered orally, but these side effects are mitigated by intranasal administration. However, as with any treatment, individual responses may vary.
	}}		}}

Lazy at 16:53, 27 March 2024

2024-03-27T16:53:56Z

← Older revision		Revision as of 09:53, 27 March 2024
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	\|category=Over-the-Counter Drugs and Supplements		\|category=Over-the-Counter Drugs and Supplements
	\|links=		\|links=
			\|toxicity_level=2
			\|toxicity_explanation=Perillyl Alcohol and Limonene, despite being under investigation for anti-cancer properties, are derived from citrus oils and generally are not associated with severe toxic effects. They do result in some gastro-intestinal side effects when administered orally, but these side effects are mitigated by intranasal administration. However, as with any treatment, individual responses may vary.
	}}		}}

Lazy: Created page with "{{TreatmentInfo |drug_name=Perillyl Alcohol/Limonene |FDA_approval=No (Under investigation for anti-cancer properties) |used_for=Investigational use in recurrent glioma treatment |clinical_trial_phase=Early-stage clinical trials, including studies in Brazil for recurrent glioma |common_side_effects=Gastro-intestinal side effects when administered orally; intranasal administration used to mitigate this |OS_with=Primary GBM: median survival of 5.9 months; Secondary GBM: me..."

2024-03-21T12:03:10Z

Created page with "{{TreatmentInfo |drug_name=Perillyl Alcohol/Limonene |FDA_approval=No (Under investigation for anti-cancer properties) |used_for=Investigational use in recurrent glioma treatment |clinical_trial_phase=Early-stage clinical trials, including studies in Brazil for recurrent glioma |common_side_effects=Gastro-intestinal side effects when administered orally; intranasal administration used to mitigate this |OS_with=Primary GBM: median survival of 5.9 months; Secondary GBM: me..."

New page

{{TreatmentInfo
|drug_name=Perillyl Alcohol/Limonene
|FDA_approval=No (Under investigation for anti-cancer properties)
|used_for=Investigational use in recurrent glioma treatment
|clinical_trial_phase=Early-stage clinical trials, including studies in Brazil for recurrent glioma
|common_side_effects=Gastro-intestinal side effects when administered orally; intranasal administration used to mitigate this
|OS_with=Primary GBM: median survival of 5.9 months; Secondary GBM: median survival of 11.2 months
|PFS_with=Initial report on recurrent GBM patients showed a PFS-6 value of 48%
|usefulness_rating=3
|notes=Perillyl Alcohol and Limonene, derived from citrus oils, have shown potential as anti-cancer agents. Clinical trials have explored their efficacy, particularly through intranasal administration to avoid gastro-intestinal side effects. Early findings suggest a degree of effectiveness in stabilizing disease and extending survival in recurrent GBM patients, with noted variance based on tumor type and location. Further research is needed to fully understand their therapeutic potential and optimal administration method.
|category=Over-the-Counter Drugs and Supplements
|links=
}}