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	<id>http://glioblastomatreatments.wiki:80/index.php?action=history&amp;feed=atom&amp;title=Hyperthermia</id>
	<title>Hyperthermia - Revision history</title>
	<link rel="self" type="application/atom+xml" href="http://glioblastomatreatments.wiki:80/index.php?action=history&amp;feed=atom&amp;title=Hyperthermia"/>
	<link rel="alternate" type="text/html" href="http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;action=history"/>
	<updated>2026-04-12T12:41:44Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.41.0</generator>
	<entry>
		<id>http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=94240&amp;oldid=prev</id>
		<title>Lazy at 08:31, 18 January 2025</title>
		<link rel="alternate" type="text/html" href="http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=94240&amp;oldid=prev"/>
		<updated>2025-01-18T08:31:22Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 01:31, 18 January 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l16&quot;&gt;Line 16:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 16:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|notes=Hyperthermia treatment involves raising the temperature of tumor tissues to enhance the effectiveness of conventional cancer therapies such as radiation and chemotherapy. This method leverages heat to induce cellular stress and damage in cancer cells, making them more susceptible to other treatments. For glioblastoma, an aggressive brain tumor, hyperthermia has shown potential in improving treatment outcomes and extending patient survival.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|notes=Hyperthermia treatment involves raising the temperature of tumor tissues to enhance the effectiveness of conventional cancer therapies such as radiation and chemotherapy. This method leverages heat to induce cellular stress and damage in cancer cells, making them more susceptible to other treatments. For glioblastoma, an aggressive brain tumor, hyperthermia has shown potential in improving treatment outcomes and extending patient survival.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|links=https://consultqd.clevelandclinic.org/turning-up-the-heat-on-glioblastoma-with-thermal-medicine/, https://brio-medical.com/hyperthermia-activation-in-treating-glioblastoma/, https://cancer.ucsf.edu/research/clinical-trials&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|links=https://consultqd.clevelandclinic.org/turning-up-the-heat-on-glioblastoma-with-thermal-medicine/, https://brio-medical.com/hyperthermia-activation-in-treating-glioblastoma/, https://cancer.ucsf.edu/research/clinical-trials&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|overview=Hyperthermia is an investigational treatment for Glioblastoma Multiforme (GBM) that aims to improve survival rates by enhancing the efficacy of radiation and chemotherapy, with clinical trials indicating potential benefits in overall and progression-free survival. While it can cause localized discomfort and may risk damage to surrounding healthy tissue, these effects are generally manageable, earning hyperthermia a usefulness rating of 4.&lt;/ins&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Lazy</name></author>
	</entry>
	<entry>
		<id>http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=1958&amp;oldid=prev</id>
		<title>Lazy at 17:05, 17 May 2024</title>
		<link rel="alternate" type="text/html" href="http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=1958&amp;oldid=prev"/>
		<updated>2024-05-17T17:05:21Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 10:05, 17 May 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l11&quot;&gt;Line 11:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 11:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|usefulness_rating=4&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|usefulness_rating=4&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|usefulness_explanation=Hyperthermia has shown potential in enhancing the effectiveness of radiation and chemotherapy, improving overall survival and progression-free survival rates in glioblastoma patients.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|usefulness_explanation=Hyperthermia has shown potential in enhancing the effectiveness of radiation and chemotherapy, improving overall survival and progression-free survival rates in glioblastoma patients.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|toxicity_level=&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Manageable with advanced monitoring techniques&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|toxicity_level=&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;3&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|toxicity_explanation=While hyperthermia can cause discomfort and risk damage to healthy tissues, these effects are generally manageable with precise control and monitoring.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|toxicity_explanation=While hyperthermia can cause discomfort and risk damage to healthy tissues, these effects are generally manageable with precise control and monitoring.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|clinical_trial_explanation=Several clinical trials have investigated the benefits of hyperthermia for glioblastoma. A prospective randomized trial at UCSF combined hyperthermia with brachytherapy, showing a significant survival benefit. Other studies are exploring hyperthermia with gold nanoparticles for targeted heating, potentially increasing efficacy while minimizing damage to healthy tissues.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|notes=Hyperthermia treatment involves raising the temperature of tumor tissues to enhance the effectiveness of conventional cancer therapies such as radiation and chemotherapy. This method leverages heat to induce cellular stress and damage in cancer cells, making them more susceptible to other treatments. For glioblastoma, an aggressive brain tumor, hyperthermia has shown potential in improving treatment outcomes and extending patient survival.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|notes=Hyperthermia treatment involves raising the temperature of tumor tissues to enhance the effectiveness of conventional cancer therapies such as radiation and chemotherapy. This method leverages heat to induce cellular stress and damage in cancer cells, making them more susceptible to other treatments. For glioblastoma, an aggressive brain tumor, hyperthermia has shown potential in improving treatment outcomes and extending patient survival.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|links=https://consultqd.clevelandclinic.org/turning-up-the-heat-on-glioblastoma-with-thermal-medicine/, https://brio-medical.com/hyperthermia-activation-in-treating-glioblastoma/, https://cancer.ucsf.edu/research/clinical-trials&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|links=https://consultqd.clevelandclinic.org/turning-up-the-heat-on-glioblastoma-with-thermal-medicine/, https://brio-medical.com/hyperthermia-activation-in-treating-glioblastoma/, https://cancer.ucsf.edu/research/clinical-trials&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Lazy</name></author>
	</entry>
	<entry>
		<id>http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=1956&amp;oldid=prev</id>
		<title>Lazy: Created page with &quot;{{TreatmentInfo |drug_name=Hyperthermia |FDA_approval=Investigational |used_for=Glioblastoma Multiforme (GBM) |clinical_trial_phase=Phase I/II |common_side_effects=Localized discomfort, potential damage to surrounding healthy tissue |OS_without=Standard progression statistics for GBM |OS_with=Extended survival reported in some clinical trials |PFS_without=Standard progression statistics for GBM |PFS_with=Improved progression-free survival in combination with other treatm...&quot;</title>
		<link rel="alternate" type="text/html" href="http://glioblastomatreatments.wiki:80/index.php?title=Hyperthermia&amp;diff=1956&amp;oldid=prev"/>
		<updated>2024-05-17T17:03:54Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;{{TreatmentInfo |drug_name=Hyperthermia |FDA_approval=Investigational |used_for=Glioblastoma Multiforme (GBM) |clinical_trial_phase=Phase I/II |common_side_effects=Localized discomfort, potential damage to surrounding healthy tissue |OS_without=Standard progression statistics for GBM |OS_with=Extended survival reported in some clinical trials |PFS_without=Standard progression statistics for GBM |PFS_with=Improved progression-free survival in combination with other treatm...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{TreatmentInfo&lt;br /&gt;
|drug_name=Hyperthermia&lt;br /&gt;
|FDA_approval=Investigational&lt;br /&gt;
|used_for=Glioblastoma Multiforme (GBM)&lt;br /&gt;
|clinical_trial_phase=Phase I/II&lt;br /&gt;
|common_side_effects=Localized discomfort, potential damage to surrounding healthy tissue&lt;br /&gt;
|OS_without=Standard progression statistics for GBM&lt;br /&gt;
|OS_with=Extended survival reported in some clinical trials&lt;br /&gt;
|PFS_without=Standard progression statistics for GBM&lt;br /&gt;
|PFS_with=Improved progression-free survival in combination with other treatments&lt;br /&gt;
|usefulness_rating=4&lt;br /&gt;
|usefulness_explanation=Hyperthermia has shown potential in enhancing the effectiveness of radiation and chemotherapy, improving overall survival and progression-free survival rates in glioblastoma patients.&lt;br /&gt;
|toxicity_level=Manageable with advanced monitoring techniques&lt;br /&gt;
|toxicity_explanation=While hyperthermia can cause discomfort and risk damage to healthy tissues, these effects are generally manageable with precise control and monitoring.&lt;br /&gt;
|notes=Hyperthermia treatment involves raising the temperature of tumor tissues to enhance the effectiveness of conventional cancer therapies such as radiation and chemotherapy. This method leverages heat to induce cellular stress and damage in cancer cells, making them more susceptible to other treatments. For glioblastoma, an aggressive brain tumor, hyperthermia has shown potential in improving treatment outcomes and extending patient survival.&lt;br /&gt;
|links=https://consultqd.clevelandclinic.org/turning-up-the-heat-on-glioblastoma-with-thermal-medicine/, https://brio-medical.com/hyperthermia-activation-in-treating-glioblastoma/, https://cancer.ucsf.edu/research/clinical-trials&lt;br /&gt;
}}&lt;/div&gt;</summary>
		<author><name>Lazy</name></author>
	</entry>
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